Adjust to Target in Type 2 Diabetes: Comparison of a simple algorithm with carbohydrate counting for adjustment of mealtime insulin glulisine

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Adjust To Target In Type 2 Diabetes: Comparison Of A Simple Algorithm To Carbohydrate Counting For Adjustment Of Mealtime Insulin Glulisine

Objective: Carbohydrate counting is an effective approach to mealtime insulin adjustment in type 1 diabetes, but has not been rigorously assessed in type 2 diabetes. Research and Design Methods: This 24-week, multicenter, randomized, controlled study compared two algorithms for adjusting mealtime (glulisine) insulin along with a standard algorithm for adjusting background (glargine) insulin in ...

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Adjust to Target in Type 2 Diabetes

OBJECTIVE Carbohydrate counting is an effective approach to mealtime insulin adjustment in type 1 diabetes but has not been rigorously assessed in type 2 diabetes. We sought to compare an insulin-to-carbohydrate ratio with a simple algorithm for adjusting the dose of prandial insulin glusiline. RESEARCH AND DESIGN METHODS This 24-week, multicenter, randomized, controlled study compared two al...

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Randomized Comparison of Pramlintide or Mealtime Insulin Added to Basal Insulin Treatment for Patients With Type 2 Diabetes

OBJECTIVE To compare the efficacy and safety of adding mealtime pramlintide or rapid-acting insulin analogs (RAIAs) to basal insulin for patients with inadequately controlled type 2 diabetes. RESEARCH DESIGN AND METHODS In a 24-week open-label, multicenter study, 113 patients were randomly assigned 1:1 to addition of mealtime pramlintide (120 microg) or a titrated RAIA to basal insulin and pr...

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ژورنال

عنوان ژورنال: Diabetes Care

سال: 2008

ISSN: 0149-5992,1935-5548

DOI: 10.2337/dc07-2137